Get ready for the £60m match as Eastlands plays hosts to White Hart Lane side looking to secure top four finish.
Manchester City midfielder Gareth Barry is set to return after recovering from a hamstring injury.
A hamstring injury has ended Joleon Lescott’s season but he could recover before the World Cup while Marton Fulop again replaces Shay Given in goal.
Tottenham also have goalkeeper worries with Heurelho Gomes facing a fitness test on his groin problem.
Manager Harry Redknapp will once again make a late decision on central defender Ledley King.
Injured: M Johnson & Petrov (both knee), Given (shoulder), Gonzalez (groin), Lescott (hamstring)
Doubtful: Gomes (groin), King (knee)
Injured: Corluka & Kranjcar (both ankle), Cudicini (broken wrists), Woodgate (groin) (BBC Sport)
Its a game that could be worth a fortune and one that will showcase the talents of two sides clearly going places. Tottenham go into this Eastlands fixture knowing that avoiding defeat would be considered a huge success but they are up against a Man City side with a great deal to prove.
With just a point separating the two teams and with just one other game for each side after this one the chance of a Champions League debut hangs in the balance for both sides.
What are your predictions for this momentous clash?
Highlights of meetings from times past to whet the appetite.
Tottenham 3-0 Manchester City December 2009
To see highlights of the previous meeting between the sides CLICK HERE
Tottenham 3-4 Manchester City FA Cup February 2004