Diego hoping for further World Cup success as coach to go with his sparkling playing record on the biggest stage.
After naming a weakened side for the win against Greece, Argentina coach Diego Maradona will recall the likes of Carlos Tevez, Javier Mascherano and Gonzalo Higuain.
Nicolas Burdisso could start at centre-back as Walter Samuel has not fully recovered from a thigh problem. Jonas Gutierrez will return at right-back after completing a one-game ban.
Maradona must decide whether to start with playmaker Juan Veron, who returned from injury against the Greeks, or Maxi Rodriguez. The Liverpool midfielder scored a spectacular goal in the win against Mexico at the 2006 World Cup.
Mexico defender Efrain Juarez has completed a one-game ban and may come into the starting XI, possibly at the expense of Hector Moreno. Striker Carlos Vela is back in training after a hamstring injury but is likely to begin on the bench.
One booking from suspension: Bolatti, Heinze, Mascherano (Argentina); Castro, Franco, Hernandez, Moreno, Rodriguez, Torrado (Mexico). (BBC Sport)
In a repeat of a fixture from 2006 Argentina will be looking to continue their dominance over Mexico in Johannesburg but will know that they will have to be at their best to edge past Javier Aguirre’s side to book safe passage to the World Cup Quarter Finals.
Highlights of previous World Cup 2010 matches these two have taken part in.
Greece 0-2 Argentina
Mexico 0-1 Uruguay