Sir Alex Ferguson will be looking to see his Old Trafford side bounce back from their Goodison Park blip against visitors from Ibrox.
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Manchester United pair Wayne Rooney and Rio Ferdinand are both set to return for their Champions League Group C opener against Rangers on Tuesday.
Striker Rooney, who was left out of the league game at Everton on Saturday after allegations about his private life, trained with the squad on Monday.
England defender Ferdinand is fit after a long-term knee injury and could play.
Rangers hope defender Steven Whittaker will recover from a calf injury, but Kirk Broadfoot (ankle) is doubtful.
Striker Kenny Miller, who scored a 90th-minute winner in the Scottish Premier League against Hamilton on Saturday, will return to the starting XI with recent signing Nikica Jelavic ineligible.Ferdinand has not played since May and he missed the World Cup with a knee problem he picked up training with England, but Sir Alex Ferguson seems certain to hand the 31-year-old a starting berth.
Midfielder Michael Carrick will not feature as he is still struggling with an ankle problem. (BBC Sport)
Highlights of this game will be posted on this site the moment the final whistle has been blown.
Walter Smith’s side could be in for a torrid evening as a certain Wayne Rooney may be looking to take out his off field frustrations on the Rangers tonight and Sir Alex Ferguson will be boosted also by the return of Rio Ferdinand to his back line.
Manchester United were left shaking their heads in disbelief as Everton scored two injury time goals to grab a point and Ferguson will be hoping his defence is up to the task against the Scottish champions. However Rangers haven’t had the best of time in the Champions League of late, failing to win any of their last ten matches.
That being said, the Ibrox side have started the SPL season with four wins from four and will be looking to get something from their trip to Old Trafford.
Sir Alex Ferguson’s pre-match press conference
Ferguson: No regrets about Rooney
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Highlights of recent domestic matches these two have taken part in.
Everton 3-3 Manchester United
Everton v Manchester United
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Hamilton 1-2 Rangers