Old Trafford stalwart could lose England captaincy as well due to calf injury.
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Manchester United defender Rio Ferdinand may miss the rest of the season with a calf injury.
The 32-year-old has struggled with a series of injuries in recent years as a result of a back problem.
The veteran injured his calf in the warm-up prior to the defeat at Wolves in February.
It was believed the injury would only keep the centre-back out for a few weeks but the problem is still unresolved.
Ferdinand’s inability to remain injury-free may cause him to lose the England captaincy as coach Fabio Capello wants his leader to be on the pitch, not in the treatment room.
United manager Sir Alex Ferguson last week thought Ferdinand would be back after the international break but he fears the defender may not play a part in the club’s push for a second treble in 12 years.
“Rio has been out for a few weeks now,” said Ferguson.
“We are not looking at this as a short-term situation.
“He has not started training yet. We will be lucky to get him back for some part of the season.”