Title contenders meet top four contenders at Old Trafford.
Venue: Old Trafford, Saturday 5.30pm
Last season: Man Utd 3 Tottenham 0. The Red Devils swept away a weakened Spurs side in the opening game of the season.
Referee: C Foy
This season’s matches: 4: Y5, R0, 1.25 cards per game
Odds: Man Utd 4-7, Tottenham 5-1, Draw 3-1
Subs from: De Gea, Johnstone, Buttner, Hernández, Cleverley, Welbeck, Anderson, Giggs, Powell, Macheda, Bebé, Henríquez, Fletcher
Injured: Valencia (leg, 3 Oct), Young (knee, 21 Oct), Smalling (foot, 21 Oct), Vidic (knee, Dec), Jones (knee, Dec)
Form guide (league): LWWWW
Disciplinary record: Y6 R0
Leading scorer: Van Persie 5
Subs from: Lloris, Gomes, Cudicini, Smith, Dawson, Naughton, Falqué, Huddlestone, Mason, Sigurdsson, Carroll, Townsend
Doubtful: Naughton (foot)
Injured: Adebayor (hamstring, 6 Oct), Assou-Ekotto (knee, 20 Oct), Parker (achilles, 20 Oct), Kaboul (knee, Dec), Livermore (groin, unknown)
Form guide (league): LDDWW
Disciplinary record: Y5 R1
Leading scorer: Defoe 4
Spurs’ last victory over the Red Devils was a 3-1 success in May 2001 at White Hart Lane. Manchester United veterans Ryan Giggs and Paul Scholes both started that match, the latter scoring.
Current Manchester United players such as Danny Welbeck, David de Gea, Fabio and the injured Phil Jones were not even born the last time Spurs won at Old Trafford in 1989, with Gary Linekar scoring Spurs winner. The North Londoners have lost 18 and drawn 4 of 22 visits since.
Tottenham have failed to score in four of their last six league and cup games against the Red Devils.
Ryan Giggs has scored more goals (10) against Spurs in the Premier League than versus any other opponent, including the first goal in this fixture in the Premier League era in September 1992.
The Red Devils have been awarded a penalty in each of their last three league matches. The last Premier League club to get four in a row was Arsenal in 2007.
Wayne Rooney has scored seven goals in his last eight Premier League appearances against Tottenham, and five in the last five.
Robin van Persie is set to make his 200th Premier League appearance. He scored five goals and made four assists in his last six league home games against Tottenham while at Arsenal.
The win over QPR gave boss Andre Villas-Boas back-to-back wins in the Premier League for the first time since January, when his then-Chelsea side beat Wolves 2-1 away and Sunderland 1-0 at home.
Tottenham have scored a league-high 88% of their goals in the second half this season.
Jermain Defoe has had more shots than any other player in the Premier League this season (31) and has had the most on target (nine). He has four goals and an assist in five league appearances and is currently on 199 club career goals.
Prediction: 3-1. Manchester United to win it comfortably. Spurs never get anything at Old Trafford but have certainly been unlucky over the years.
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