The Catalans come to the Etihad Stadium for the first time.
For the first time in history Manchester City and Barcelona go head-to-head in a competitive match, as the two sides face each other in the last-16 of the Champions League.
It’s a huge fixture in the competition, which many are billing as the tie of the round and it’s difficult to predict the outcome.
Here’s how CaughtOffside thinks Barca will line-up against the Citizens, as Gerardo Martino welcomes back some key players.
Goalkeeper – Victor Valdes
With the Spaniard fit there’s not dispute that the 32-year-old will start between the sticks.
Right-back – Dani Alves
Perhaps the best attacking full-back in world football, although the Brazilian can be suspect in defence and David Silva should look to exploit this.
Centre-back – Carles Puyol
With question marks over Javier Mascherano’s form and fitness, the Catalans’ veteran captain should get the nod to start at the back.
Centre-back – Gerard Pique
The most important player in Martino’s back four, with the Spain international providing some much needed leadership and talent in what is often a leaky defence.
Left-back – Adriano
Having impressed in recent times on the left side the Brazilian is likely to keep his place ahead of Jordi Alba – particularly away from home due to the 29-year-old’s superior defensive nous.