Old Trafford side put out most costly eleven in English top tier history.
Man United fielded the most expensive starting line-up in Premier League history as they faced local rivals Man City, though this was clearly not enough to avoid defeat.
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Here is a closer look at the XI and the merits, or otherwise, of each player.
David de Gea: £18.9m
Started his Old Trafford career a little shakily but is arguably now one of the best keepers in the Premier League.