Valencia fell to a debilitating 2-0 loss to Celta Vigo at the Mestalla on Sunday evening which still leaves them just six points above the relegation zone.
It was a poor performance from the hosts as goalkeeper Mathew Ryan was forced into making countless crucial saves for his side in order to avoid the scoreline becoming embarrassing.
Although the home side did have a few chances of their own, they were simply outplayed by their rivals as the pressure continues to build on Gary Neville.
Following their elimination from the Europa League, all the focus will now be switch to La Liga, and having missed out on the opportunity to open up a nine-point gap over the bottom three, they may well yet find themselves dragged back into a relegation scrap.
The white handkerchiefs were out at the full-time whistle signalling the discontent from supporters with their current coach, and after a game in which they never looked in control and ultimately ended by falling apart, it remains to be seen how long the Manchester United legend has left to save himself from being sacked.