White Hart Lane prepares for the visit of Emirates side with both sides desperate for all three points.
Tottenham club captain Ledley King is confident about making a comeback against Arsenal after a seven-week absence with a thigh injury.
Wilson Palacios begins a two-match ban, while fellow midfielder Niko Kranjcar is sidelined with an ankle injury.
Arsenal manager Arsene Wenger has confirmed forward Robin van Persie will return to the squad exactly five months after rupturing ankle ligaments.
Alex Song has not recovered from a knee problem in time to play.
Suspended: Palacios (two matches) Doubtful: King (thigh)
Injured: Cudicini (broken wrists), Jenas, Lennon & Woodgate (all groin), Kranjcar (ankle), Rose (knee)
Injured: Arshavin & Gallas (both calf), Djourou & Song (both knee), Fabregas & Ramsey (both leg), Gibbs (foot) (BBC Sport)
This north London derby has extra significance tonight as Tottenham and Arsenal desperately need all three points to aid their respective fights for a Champions League spot and Premier League title respectively. Harry Redknapp was understandably angry to see his White Hart Lane side fall to Sunderland in their last fixture, a result that was further compounded by Man City’s recent good form and their defeat at the hands of Portsmouth in the FA Cup semi-final wouldn’t have helped morale either.
Its a game that Arsenal also need to win to keep up pressure on Man United and Chelsea and the Gunners have not lost a league game against their local rivals in the last 20 meetings stretching back to late 1999. Wenger will have to do without a number of his top performers but Tottenham too will be without crucial players.
My Bet of the Daywould be on there being five or more cards shown at odds of 11/10. It may also be worth betting on a goalscoring draw and 6/1 on a 1-1 result sounds pretty good. First goalscorer odds of 10/1 on Samir Nasri or even a generous 28/1 on Sol Campbell seem like decent bets. 14/1 on Luka Modric opening the scoring is also pretty good.
My Prediction: 1-1 draw that helps neither sides cause.
Here are some highlights from north London derbies from the past that will whet your appetite.
Tottenham 5-1 Arsenal January 2008
Tottenham 4-5 Arsenal November 2004