Emirates and Anfield duo will be rested this summer.
Arsenal midfielder and Liverpool striker Andy Carroll are the surprise omissions from the England U21 squad to play in the European Championship in Denmark this summer.
Their inclusion has raised a huge debate with manager’s claiming the pair should be rested while FA officials claimed it would be good experience.
Manager Stuart Pearce seems to have been swayed by Arsene Wenger’s theory that Wilshere in particular could suffer from burn-out.
“Andy Carroll and Jack Wilshere will not be part of the Under 21 squad which travels to Denmark. Andy has been ruled out through injury,” Pearce said in a statement on the FA’s website.
“I spoke to Jack last week and he explained that while he told me in March that he wanted to be part of the squad, he now feels he is not in the best condition to take part in the finals.
“That is based on the number of games he has played for Arsenal this season, sports science data which Jack was presented with last week and concerns he has for his fitness looking ahead to next season.
“Jack has always expressed his enjoyment at being involved with the U21 squad, and while I am disappointed not to have him with us for the finals I’ve accepted the situation.”
“I am very conscious of the importance of looking after all our players, and that is why I have frequent conversations with club managers throughout the season,” he added.
“I believe that representing your country in international development tournaments can be a great advantage to players, and increases the chances of being successful at senior level.”
Pearce has selected four players with senior team experience, including Manchester City’s Micah Richards, Arsenal’s Kieran Gibbs, Manchester United’s Danny Welbeck and Sunderland’s Jordan Henderson.
Meanwhile, Frank Fielding, Michael Mancienne, Chris Smalling and Kyle Walker have also all been involved in the senior team setup.
Chelsea striker Daniel Sturridge, who impressed on loan at Bolton this season, has also been included by Pearce.
A final squad list will be submitted to Uefa on 1st June before the tournament begins for England on 12th June against Spain in Herning.
They then meet Ukraine at the same venue on 15th June and finish their Group B fixtures on 19th June against Czech Republic.
Before England travel to Denmark they will take on Norway in a warm-up fixture at Southampton’s St. Mary’s Stadium on 5th June.
Squad in full:
Fielding (Derby County), Steele (Middlesbrough), McCarthy (Reading), Bertrand (Chelsea), Gibbs (Arsenal), Jones (Blackburn) Mancienne (Chelsea), Richards (Manchester City), Smalling (Manchester United), Walker (Tottenham Hotspur), Albrighton (Aston Villa), Cleverley (Manchester United), Cork (Chelsea), Henderson (Sunderland), Lansbury (Arsenal), Muamba (Bolton Wanderers), Rodwell (Everton), Rose (Tottenham Hotspur), Sinclair (Swansea City), Delfouneso (Aston Villa), Sturridge (Chelsea), Welbeck (Manchester United), Wickham (Ipswich Town).