Gunners entertain League One Sky Blues.
Arsenal manager Arsene Wenger is expected to field a youthful side in the League Cup against Coventry.
Among those likely to feature is Nico Yennaris, who was a mascot when Arsenal last hosted Coventry 12 years ago.
Coventry could include midfielder James Bailey, who joined on a three-month loan from Derby on Tuesday.
Fellow loan signing Conor Henderson is ineligible against his parent club Arsenal, while David McGoldrick is cup-tied. (BBC Sport)
Arsenal: Martinez, Miquel, Djourou, Angha, Yennaris, Santos, Coquelin, Oxlade-Chamberlain, Walcott, Arshavin, Giroud: SUBS: Shea, Squillaci, Bellerin, Frimpong, Eisfeld, Gnabry, Chamakh
Coventry City: Murphy, Clarke, Wood, Brown, Reckord, Baker, Barton, Bailey, Moussa, Elliott, McSheffrey
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