St James’ Park plays host to Ligue 1 opposition.
Full-back Danny Simpson is back in the Newcastle squad after more than a month out with a hamstring injury.
His return is timely for the Magpies, who are likely to face Bordeaux without centre-backs Steven Taylor (calf) and Fabricio Coloccini (hamstring).
Keeper Tim Krul is still sidelined with an ankle problem, but midfielder Yohan Cabaye is in contention after recovering from a mouth infection.
Newcastle drew their opening game 0-0 against Portuguese side Maritimo.
Bordeaux are top of Group D after winning their first match 4-0 against Club Bruges.
Newcastle United: Elliot, Simpson, Williamson, Perch, Ferguson, Anita, Tiote, Cabaye, Cisse, Shola Ameobi, Obertan: SUBS: Harper, Santon, Gosling, Bigirimana, Ben Arfa, Sammy Ameobi, Ba
Bordeaux: Carrasso, Henrique, Planus, Trémoulinas, Mariano, Sané, Plasil, Obraniak, Saivet, Jussie, Gouffran
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