Emirates Stadium and Stamford Bridge outfits have their work cut out.
With the draw for the first knockout phase having been made we have decided to take a long hard look at the fixtures before assembling the 16 remaining sides in order of the likelihood of each side winning the tournament.
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A tough draw for Man City severely shortens their chances of success whilst reigning champions Real Madrid and unstoppable German force Bayern Munich benefit from relatively easy draws.
16) Schalke
15) Shakhtar Donetsk
14) AS Monaco
13) FC Basel
12) Bayer Leverkusen
11) FC Porto
10) Atletico Madrid
9) Borussia Dortmund
8) Man City
7) PSG
6) Juventus
5) Arsenal
4) Chelsea
3) Barcelona
2) Bayern Munich
1) Real Madrid