Arsene Wenger’s side take on defensively sound Ligue 1 opposition at the Emirates Stadium.
Arsenal will look to garner a solid performance from their first leg encounter with AS Monaco, ideally gaining a decent lead while refusing to allow an away goal.
The Gunners are heavy favourites in the betting market, but will have to be on their toes against a physically strong and well organised Monacos outfit.
Here are three potential crucial head to head battles that could be key on Wednesday night.
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Laurent Koscielny Vs Dimitar Berbatov
The former Tottenham and Man United man isn’t the fastest and is of course not known for tracking back, however, he does possess the class to make a life a nightmare for even the most solid centre-back.
Frenchman Koscielny is Arsenal’s most consistent defensive performer and, if delegated to mark the AS Monaco veteran, will have to be on the top of his game to prevent even the slightest whiff of a goal-scoring opportunity.