Barcelona host Man City at the Nou Camp as they aim to defend their 2-1 lead and eliminate the English champions at the last-16 round for the second successive season.
However, the La Liga table toppers were dealt a blow with Sergio Busquets unable to feature. He is replaced by Jeremy Mathieu, the only change from the team in the first leg.
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Manchester City FC news
Win or bust! Manuel Pellegrini faces SACK if Barcelona destroy Man City’s Champions League hopes
We will make Man City suffer” – Barcelona midfielder fires warning
For Manchester City, Manuel Pellegrini is reportedly aiming to save his career and looks to have learned from the first leg by going with a five man midfield in vital Champions League tie for Man City.