United are targeting the Italian to replace Paul Scholes.
Juventus general manager Guiseppe Marotta has said that the club will not be selling star midfielder Claudio Marchisio despite reported interest from Manchester United, Sky Sports reports.
Rumours have suggested that United are interested in signing Marchisio because new manager David Moyes is worried about the lack of top quality central midfielders at the club.
Paul Scholes retired last season after spending all his career at Old Trafford and doubts persist about the fitness of Darren Fletcher, whose long-term illness has kept him out of the side for a long time.
Marchisio recently stated that he would be very proud if United did make a move for him but Guiseppe Marotta has said that Juventus will try their best to keep the Italian at the club.
Marchisio? There is no meeting; there is no problem with him,” he told Sky Sport 24 Italy.
“Juventus have never thought about putting him on the market, he is an important player and we will try to keep him with us.”
Manchester United look set to sign a central midfielder this summer and Marchisio is one of several players that United have been linked with.
The club are reportedly interested in Barcelona pair Cesc Fabregas and Thiago Alcantara as well as a re-union with former player Cristano Ronaldo.