Clubs could pounce for £28m Real Madrid star.
The Italian giants could also face competition from the likes of Arsenal and Chelsea for the former Malaga man, who has emerged several times as a target for Premier League clubs.
Despite some hugely improved performances for Real last season, Isco’s place is under threat this season due to new manager Rafael Benitez favouring Gareth Bale in a more central role.
Eva Carneiro affair
Arsenal transfer rumours: Giroud & Welbeck replaced by £75m duo, Gunners in shock bid for Tottenham star & more
Premier League stats of the weekend, featuring Arsenal’s London derby record, Lukaku goals & Chelsea’s flying starts
According to Fichajes.com, this could see Los Blancos let the Spanish international leave the club for the right price before the end of the summer.