DC: Chris Smalling
A key defender for United, Chris Smalling ended last season in strong form and is likely to be first choice for Louis van Gaal’s side this season.
DC: Daley Blind
Tipped to move into a central role this season, Daley Blind seems United’s best bet to partner Smalling after some unconvincing performances from the likes of Phil Jones and Jonny Evans.
DM: Morgan Schneiderlin
Another player making his debut, Morgan Schneiderlin starts in defensive midfield after his summer switch from Southampton, playing against a club he nearly joined last year.
MC: Ander Herrera
A player fighting for his place now, Ander Herrera should still make it into the side this weekend in this central midfield three.
MC: Bastian Schweinsteiger
A hugely exciting summer signing, Bastian Schweinsteiger is in line for his first United start against Spurs at Old Trafford.